

HY-167701 · 50 mg
MedChemExpress · Cat: HY-167701
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Manufacturer product page
medchemexpress.com/obhsa.html
Description
OBHSA is a selective estrogen receptor ER? degrader. OBHSA blocks the cell cycle by degrading cyclin D1, thereby overcoming Tamoxifen HY-13757A resistance. OBHSA also triggers excessive activation of the unfolded protein response UPR by inducing an increase in intracellular reactive oxygen species, ultimately leading to cell apoptosis. In addition, OBHSA can also be used as an ER? ligand to synthesize PROTAC degraders.







