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Octyl-?-ketoglutarate
GENERAL CATALOGUE

Octyl-?-ketoglutarate

HY-114333 · 1 mg

MedChemExpress · Cat: HY-114333

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Catalog No: HY-114333
CAS No: 876150-14-0
Category: Metabolic Enzyme Protease
Pack Size: 1 mg
Brand: MedChemExpress

Description

Octyl-?-ketoglutarate 1-Octyl 2-oxopentanedioate is a stable, cell-permeable form of ?-ketoglutarate which accumulates rapidly in HEK293 cells with a dysfunctional tricarboxylic acid TCA cycle, stimulating prolyl hydroxylase PHD activity. In addition, Octyl-?-ketoglutarate competitively blocks succinate- or fumarate-mediated inhibition of PHD.

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