

HY-13106 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-13106
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Manufacturer product page
medchemexpress.com/EMA401.html
Description
Olodanrigan EMA401 is a highly selective, orally active, peripherally restricted angiotensin II type 2 receptor AT2R antagonist. It is under development as a neuropathic pain therapeutic agent. Olodanrigan EMA401 analgesic action appears to involve inhibition of augmented AngII/AT2R induced p38 and p42/p44 MAPK activation, and hence inhibition of DRG neuron hyperexcitability and sprouting of DRG neurons.







