GENERAL CATALOGUE
OM-153
HY-145267 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-145267
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medchemexpress.com/om-153.htmlCatalog No: HY-145267
CAS No: 2406278-81-5
Category: Cell Cycle DNA Damage
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
OM-153 is a potent and orally active tankyrase inhibitor with IC50s of 13 nM and 2 nM for tankyrase 1 and tankyrase 2 TNKS1/2 , respectively. OM-153 inhibits luciferase-based Wnt/?-catenin signaling reporter activity with an IC50 value of 0.63 nM. OM-153 shows inhibition of Wnt/?-catenin signaling and proliferation in COLO 320DM.