GENERAL CATALOGUE
Omburtamab
HY-P99157 · 1 mg
MedChemExpress · Cat: HY-P99157
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medchemexpress.com/omburtamab.html
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Catalog No: HY-P99157
CAS No: 1895083-75-6
Category: Immunology Inflammation
Pack Size: 1 mg
Brand: MedChemExpress
Description
Omburtamab is a humanized monoclonal antibody targeting B7-H3 CD276 . Omburtamab selectively binds to B7-H3 highly expressed on the surface of tumor cells and activates anti-tumor immune responses mediated by T cells and natural killer NK cells. Omburtamab can promote the specific infiltration of CAR-T cells into tumors, enhance the killing function of NK cells through the CD16 signaling pathway, and regulate tumor cell glucose metabolism such as inhibiting the Warburg effect . Omburtamab has the potential to inhibit solid tumors such as non-small cell lung cancer NSCLC .
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