GENERAL CATALOGUE
ON1231320
HY-100789 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-100789
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Catalog No: HY-100789
CAS No: 1312471-39-8
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
ON1231320 is a highly specific polo like kinase 2 PLK2 inhibitor with an IC50 of 0.31 ?M. ON1231320 blocks tumor cell cycle progression in the G2/M phase in mitosis, causing apoptotic cell death. ON1231320, an arylsulfonyl pyrido-pyrimidinone, has antitumor activity.
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