GENERAL CATALOGUE
Onalespib
HY-14463 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-14463
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medchemexpress.com/AT13387.html
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Catalog No: HY-14463
CAS No: 912999-49-6
Category: Cell Cycle DNA Damage
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
Onalespib AT13387 is a potent and cross the blood-brain barrier heat-shock-protein-90 Hsp90 inhibitor. Onalespib inhibits the proliferation, survival and migration. Onalespib decreases the expression of EGFR, p-EGFR, AKT, P-AKT, ERK1/2, P-ERK1/2, S6, P-S6 protein. Onalespib shows antitumor activity. Onalespib has the potential for the research of non-small cell lung cancer NSCLC .