GENERAL CATALOGUE
ONC213
HY-164515 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-164515
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medchemexpress.com/onc213.html
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Catalog No: HY-164515
CAS No: 1977540-13-8
Category: Apoptosis
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
ONC213 is an orally active ?KGDH inhibitor. ONC213 can suppress mitochondrial respiration and elevate ?-ketoglutarate levels by inhibiting ?KGDH activity. ONC213 can induce cells apoptosis by inducing mitochondrial stress response and inhibiting translation of MCL-1. ONC213 can be used for the research of cancer, such as acute myeloid leukemia research AML .
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