GENERAL CATALOGUE
ONO-2952
HY-111191 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-111191
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Catalog No: HY-111191
CAS No: 895169-20-7
Category: GPCR G Protein
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
ONO-2952 is a potent, selective and orally active translocator protein 18 kDa TSPO antagonist with Ki of 0.33-9.30 nM for rat and human TSPO. ONO-2952 is more selective for TSPO than other receptors, transporters, ion channels and enzymes. ONO-2952 exerts its anti-stress effects through inhibition of excessive activation of noradrenergic system in the brain without the amnesic effect. ONO-2952 has the potential for irritable bowel syndrome treatment.
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