GENERAL CATALOGUE
OPB-171775
HY-162730 · 5 mg
MedChemExpress · Cat: HY-162730
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Manufacturer product page
medchemexpress.com/opb-171775.htmlCatalog No: HY-162730
CAS No: 2131210-15-4
Category: Metabolic Enzyme Protease
Pack Size: 5 mg
Brand: MedChemExpress
Description
OPB-171775 is an orally active molecular glue. OPB-171775 forms ternary complex with phosphodiesterase 3A PDE3A and schlafen family member 12 SLFN12 . OPB-171775 causes SLFN12 RNase-mediated cell death, activates SLFN12 RNase-associated GCN2 signaling pathway. OPB-171775 exhibits significant efficacy against gastrointestinal stromal tumor.
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