GENERAL CATALOGUE
Oritinib mesylate
HY-139920A · 50 mg
MedChemExpress · Cat: HY-139920A
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medchemexpress.com/oritinib-mesylate.html
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Catalog No: HY-139920A
CAS No: 2180164-79-6
Category: JAK STAT Signaling
Pack Size: 50 mg
Brand: MedChemExpress
Description
Oritinib SH-1028 mesylate is a selective, orally active, and pyrimidine-based irreversible inhibitor of EGFR with an IC50 of 18 nM. Oritinib SH-1028 mesylate exhibits potent activity against EGFR sensitive and resistant T790 M mutations. Oritinib SH-1028 mesylate significantly inhibits proliferation of tumor cells with EGFR sensitive and resistant mutation.
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