

HY-N0157 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-N0157
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medchemexpress.com/Orotic-acid.htmlDescription
Orotic acid 6-Carboxyuracil , a precursor in biosynthesis of pyrimidine nucleotides and RNA, is released from the mitochondrial dihydroorotate dehydrogenase DHODH for conversion to UMP by the cytoplasmic UMP synthase enzyme. Orotic acid is a marker for measurement in routine newborn screening for urea cycle disorders. Orotic acid can induce hepatic steatosis and hepatomegaly in rats.





