GENERAL CATALOGUE
Osilodrostat phosphate
HY-16276A · 5 mg
MedChemExpress · Cat: HY-16276A
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Catalog No: HY-16276A
CAS No: 1315449-72-9
Category: Metabolic Enzyme Protease
Pack Size: 5 mg
Brand: MedChemExpress
Description
Osilodrostat LCI699 phosphate is a potent, orally active11?-hydroxylase CYP11B1 inhibitor with an IC50 value of 35 nM. Osilodrostat phosphate is a potent, orally aldosterone synthase CYP11B2 inhibitor with IC50 values of 0.7 nM and 160 nM for human aldosterone synthase and rat aldosterone synthase, respectively. Osilodrostat phosphate inhibits aldosterone and corticosterone synthesis. Osilodrostat phosphate has blood pressure lowering ability. Osilodrostat phosphate can be used for research of Cushing syndrome CS .
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