OSR1 Rabbit Polyclonal Antibody

Description

EnkiLife offers the OSR1 Rabbit Polyclonal Antibody. This antibody reacts with Human,Mouse species and is suitable for IHC,ICC/IF,ELISA application. Alternative Names of Immunogen: OXSR1; KIAA1101; OSR1; Serine/threonine-protein kinase OSR1; Oxidative stress-responsive 1 protein. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: IHC 1:100-1:300,ICC/IF 1:50-1:200,ELISA 1:5000-1:10000 Background: The product of this gene belongs to the Ser/Thr protein kinase family of proteins. It regulates downstream kinases in response to environmental stress, and may play a role in regulating the actin cytoskeleton. [provided by RefSeq, Jul 2008],catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:By autophosphorylation on threonine.,function:Regulates downstream kinases in response to environmental stress. May also have a function in regulating the actin cytoskeleton.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Binds to and phosphorylates PAK1. Interacts with chloride channel proteins SLC12A6 isoform 2, SLC12A1 and SLC12A2 but not with SLC12A4 and SLC12A7, possibly establishing sensor/signaling modules that initiate the cellular response to environmental stress. Binds to and phosphorylates RELL1, RELL2 AND RELT.,tissue specificity:Ubiquitously expressed in all tissue examined.,