OX1a

Description

OX1a OLC20 is an Orco antagonist with non-competitive activity that inhibits the activation of oxygen odor receptors ORs . OX1a is able to reduce the activation of ORs by competitively inhibiting the effects of Orco agonists. OX1a also shows non-competitive inhibition of odor molecules, which may affect the olfactory-mediated behavior of insects. Through structural optimization, OX1a analogs have shown higher antagonistic potency, indicating that this type of compound may have application potential in a wide range of insect species.