GENERAL CATALOGUE
Oxaprozin-d10
HY-W709448 · 50 mg
MedChemExpress · Cat: HY-W709448
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Manufacturer product page
medchemexpress.com/oxaprozin-d10.htmlCatalog No: HY-W709448
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
Oxaprozin-d10 Oxaprozinum-d10; Wy21743-d10 is the deuterium labeled Oxaprozin HY-B0808 . Oxaprozin is an orally active and potent COX inhibitor, with IC50 values of 2.2 ?M for human platelet COX-1 and and 36 ?M for IL-1-stimulated human synovial cell COX-2, respectively. Oxaprozin also inhibits the activation of NF-?B. Oxaprozin induces cell apoptosis. Oxaprozin shows anti-inflammatory activity. Oxaprozin-mediated inhibition of the Akt/IKK/NF-?B pathway contributes to its anti-inflammatory properties.
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