GENERAL CATALOGUE
Oxaprozin potassium
HY-B0808A · 50 mg
MedChemExpress · Cat: HY-B0808A
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Catalog No: HY-B0808A
CAS No: 174064-08-5
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
Oxaprozin potassium is an orally active and potent COX inhibitor, with IC50 values of 2.2 ?M for human platelet COX-1 and and 36 ?M for IL-1-stimulated human synovial cell COX-2, respectively. Oxaprozin potassium also inhibits the activation of NF-?B. Oxaprozin potassium induces cell apoptosis. Oxaprozin potassium shows anti-inflammatory activity. Oxaprozin potassium-mediated inhibition of the Akt/IKK/NF-?B pathway contributes to its anti-inflammatory properties.
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