GENERAL CATALOGUE
P162-0948
HY-170813 · 50 mg
MedChemExpress · Cat: HY-170813
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medchemexpress.com/p162-0948.htmlCatalog No: HY-170813
CAS No: 1358201-44-1
Category: Cell Cycle DNA Damage
Pack Size: 50 mg
Brand: MedChemExpress
Description
P162-0948 is a selective CDK8 inhibitor with an IC50 value of 50.4 nM. P162-0948 reduces cell migration and protein expression of EMT-related proteins in A549 human alveolar epithelial cell lines. P162-0948 reduces phosphorylation of Smad, which suggests disruption of the TGF-?/Smad signaling pathway. P162-0948 is promising for research of pulmonary fibrosis.