p38-? MAPK-IN-8

Description

p38-? MAPK-IN-8 Compound 13 is a lipophilic cationic derivative. p38-? MAPK-IN-8 is cytotoxic to various tumor cells, and can induce cell cycle arrest, apoptosis, increase reactive oxygen species ROS production, and induce mitochondrial membrane potential depolarization. The antitumor activity of p38-? MAPK-IN-8 may be related to p38? MAPK pathway, which can be used in the study of cancer.