p52 S6 kinase Rabbit Polyclonal Antibody

Description

EnkiLife offers the p52 S6 kinase Rabbit Polyclonal Antibody. This antibody reacts with Human,Mouse species and is suitable for WB,ICC/IF,ELISA application. Alternative Names of Immunogen: RPS6KC1; RPK118; Ribosomal protein S6 kinase delta-1; S6K-delta-1; 52 kDa ribosomal protein S6 kinase; Ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein; SPHK1-binding protein. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2000,ICC/IF 1:200-1:1000,ELISA 1:10000-1:20000 Background: catalytic activity:ATP + a protein = ADP + a phosphoprotein. caution:Instead of Lys-820, Arg-820 is found at the binding site. domain:The first protein kinase domain appears to be a pseudokinase domain as it does not contain the classical characteristics, such as the ATP-binding motif, ATP-binding site and active site. function:May be involved in transmitting sphingosine-1 phosphate (SPP)-mediated signaling into the cell. similarity:Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. S6 kinase subfamily. similarity:Contains 1 MIT domain. similarity:Contains 1 PX (phox homology) domain. similarity:Contains 2 protein kinase domains. subcellular location:Also found in some small dot-like or ring-shaped early endosome structures. subunit:Interacts with SPHK1 and phosphatidylinositol 3-phosphate. tissue specificity:Highly expressed in testis, skeletal muscle, brain, heart, placenta, kidney and liver and weakly expressed in thymus, small intestine, lung and colon. Research Area:Regulates Angiogenesis; Insulin Receptor; B Cell Receptor; AMPK