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p53 Activator 14
GENERAL CATALOGUE

p53 Activator 14

HY-170591 · 50 mg

MedChemExpress · Cat: HY-170591

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Catalog No: HY-170591
CAS No: 2922588-44-9
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress

Description

p53 Activator 14 Compound 7A is a derivative of Neratinib HY-32721 , that induces DNA damage, activates p53, and inhibits the proliferation of multi cancer cells IC50=7.21 ?M for HCT116 cell . p53 Activator 14 inhibits the adhesion, migration and invasion of HCT116, arrests the cell cycle, and induces apoptosis. p53 Activator 14 inhibits angiogenesis and exhibits antitumor efficacy in chick chorioallantoic membrane CAM model.

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