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p53-MDM2-IN-6
GENERAL CATALOGUE

p53-MDM2-IN-6

HY-162927 · 50 mg

MedChemExpress · Cat: HY-162927

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medchemexpress.com/p53-mdm2-in-6.html
Catalog No: HY-162927
CAS No: 1054506-59-0
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress

Description

p53-MDM2-IN-6 Compound 10a , a LSM-83177 hydrazone analog, is a potent p53-MDM2 inhibitor with an IC50 value of 11.08 AAasAasAAmug/mL. p53-MDM2-IN-6 arrests the cell cycle in the S phase and induces early and late Apoptosis with antiproliferative activity against HT29 cell lines with an IC50 value of 10.44 AAasAasAAmug/mL. p53-MDM2-IN-6 inhibits p53-MDM2 interaction with increment in p-53 level and decrease the expression of GST enzymes. p53-MDM2-IN-6 is promising for research of colorectal cancer.

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