GENERAL CATALOGUE
p53 Stabilizer 2
HY-172915 · 50 mg
MedChemExpress · Cat: HY-172915
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Catalog No: HY-172915
CAS No: 2531685-87-5
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
p53 Stabilizer 2 Compound 17a16 is a p53 stabilizer. p53 Stabilizer 2 induces S-phase arrest and apoptosis in both p53-proficient and p53-deficient cancer cells. p53 Stabilizer 2 induces mitochondrial stress and activates two checkpoint pathways: NA-PKcs-dependent p53 stabilization and ATR-Chk1 axis activation. p53 Stabilizer 2 inhibits tumor growth in p53-deficient xenograft model.
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