GENERAL CATALOGUE
P62-mediated mitophagy inducer
HY-115576 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-115576
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medchemexpress.com/p62-mediated-mitophagy-inducer.htmlCatalog No: HY-115576
CAS No: 1809031-84-2
Category: Autophagy
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
P62-mediated mitophagy inducer PMI is a P62-mediated mitophagy activator. P62-mediated mitophagy inducer activates mitochondrial autophagy without recruitment of Parkin or collapse of the mitochondrial membrane potential and remains active in cells lacking a fully functional PINK1/Parkin pathway. P62-mediated mitophagy inducer serves as a pharmacological tool to study the molecular mechanisms of mitosis, avoiding toxicity and some of the non-specific effects associated with the sudden dissipation of mitochondria lacking membrane potential.
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