

HY-151799 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-151799
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medchemexpress.com/antitumor-agent-81.htmlDescription
P62-RNF168 agonist-1 compound 5a is a low cytotoxicity P62-RNF168 agonist that enhances the interaction between P62 and RNF168. P62-RNF168 agonist-1 induces a reduction in H2A ubiquitination mediated by RNF168 and impairs homologous recombination-mediated DNA repair. P62-RNF168 agonist-1 also inhibits the growth of xenograft tumors in mice in a dose-dependent manner.







