GENERAL CATALOGUE
PAA-38
HY-172773 · 50 mg
MedChemExpress · Cat: HY-172773
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medchemexpress.com/paa-38.html
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Catalog No: HY-172773
Category: Anti-infection
Pack Size: 50 mg
Brand: MedChemExpress
Description
PAA-38 is a highly potent selective inhibitor targeting bacterial prolyl-tRNA synthetase ProRS . PAA-38 againsts Pseudomonas aeruginosa ProRS PaProRS with a Kd value of 0.399 nM and an IC50 value of 4.97 nM. PAA-38 againsts human cytoplasmic ProRSs HsProRS with an IC50 value of 35.5 nM. PAA-38 demonstrates an in vitro antibacterial activity of minimum inhibitory concentration MIC = 4-8 ?g/mL.
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