GENERAL CATALOGUE
PACMA 31
HY-100433 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-100433
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medchemexpress.com/pacma-31.htmlCatalog No: HY-100433
CAS No: 1401089-31-3
Category: Cell Cycle DNA Damage
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
PACMA 31 is an irreversible, orally active protein disulfide isomerase PDI inhibitor with an IC50 of 10 ?M. PACMA 31 forms a covalent bond with the active site cysteines of PDI. PACMA 31 shows tumor targeting ability and significantly suppresses ovarian tumor growth without causing toxicity to normal tissues. PACMA 31 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition CuAAc with molecules containing Azide groups.
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