

HY-139088 · 500 g
MedChemExpress · Cat: HY-139088
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medchemexpress.com/pad3-in-1.htmlDescription
PAD3-IN-1 compound 14b is an inhibitor of protein arginine deiminase PAD and is more than 10-fold more selective for PAD3 than PAD 1, 2, and 4. The IC50 values of PAD3-IN-1 for PAD 1, 2, 3, and 4 are 120, 27.5, 4.5, and 30.5 ?M, respectively. And PAD3 is a PAD isoform associated with neurodegenerative responses to spinal cord injury, and PAD3-IN-1 could be used to study PAD-related neurological diseases.