

HY-144069 · 50 mg
MedChemExpress · Cat: HY-144069
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medchemexpress.com/pan-trk-in-3.htmlDescription
Pan-Trk-IN-3 Compound 11g is a potent inhibitor of pan-Trk and their drug-resistant mutants with IC50 values of 2, 3, 2, 21, 26, 5, 7 and 6 nM against TrkA, TrkB, TrkC, TrkAG595R, TrkAG667C, TrkAG667S, TrkAF589L and TrkCG623R, respectively. Pan-Trk-IN-3 displays excellent antitumor activity and induces apoptosis.







