

HY-159896 · 50 mg
MedChemExpress · Cat: HY-159896
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medchemexpress.com/par4-antagonist-8.htmlDescription
PAR4 antagonist 8 Compound 20f is an effective, orally active, and selective PAR4 antagonist with an IC50 value of 15.32 nM. PAR4 antagonist 8 exhibits favorable pharmacokinetic properties. PAR4 antagonist 8 not only effectively inhibits human platelet aggregation induced by PAR4 agonists IC50 = 6.39 nM but also inhibits mouse platelet aggregation. PAR4 antagonist 8 can be used in antithrombotic research.







