GENERAL CATALOGUE
Paritaprevir dihydrate
HY-12594A · 50 mg
MedChemExpress · Cat: HY-12594A
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medchemexpress.com/paritaprevir-dihydrate.htmlCatalog No: HY-12594A
CAS No: 1456607-71-8
Category: Anti-infection
Pack Size: 50 mg
Brand: MedChemExpress
Description
Paritaprevir ABT-450 dihydrate is a potent, orally active and antiviral non-structural protein 3/4A NS3/4A protease inhibitor with EC50s of 1 and 0.21 nM against HCV 1a and 1b, respectively. Paritaprevir dihydrate is also a SARS-CoV 3CLpro inhibitor with an IC50 of 1.31 ?M. Paritaprevir dihydrate is metabolized primarily by cytochrome P450 CYP 3A. The plasma concentration and half-life of Paritaprevir dihydrate can be enhanced by Ritonavir a CYP450 inhibitor .
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