PARP Mouse Monoclonal Antibody

Description

EnkiLife offers the PARP Mouse Monoclonal Antibody. This antibody reacts with Human species and is suitable for WB,ELISA,FC application. Alternative Names of Immunogen: PARP; PPOL; ADPRT; ADPRT1; PARP-1; pADPRT-1; PARP1. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2000,ELISA 1:5000-1:20000,FC 1:200-1:400 Background: This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. Research Area: Apoptosis