

HY-163817 · 50 mg
MedChemExpress · Cat: HY-163817
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medchemexpress.com/parp1-2-in-3.htmlDescription
PARP1/2-IN-3 Compound 29 is an orally active inhibitor for PARP 1 and PARP 2 with IC50 of 0.2235 nM and <0.001 nM. PARP1/2-IN-3 inhibits the proliferation of Capan-1 wildtype, AZD2281 or BMN673 resistant cells with IC50 of 1.82-9.98 nM. PARP1/2-IN-3 exhibits antitumor efficacy in mice.