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PARP1/2/TNKS1/2-IN-1
GENERAL CATALOGUE

PARP1/2/TNKS1/2-IN-1

HY-146336 · 1 mg

MedChemExpress · Cat: HY-146336

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Catalog No: HY-146336
CAS No: 2243453-32-7
Category: Apoptosis
Pack Size: 1 mg
Brand: MedChemExpress

Description

PARP1/2/TNKS1/2-IN-1 Compound I-9 is a dual PARP-1, PARP-2, TNKS1 and TNKS2 inhibitor with IC50 values of 0.25 nM, 1.2 nM, 13.5 nM and 4.15 nM against PARP-1, PARP-2, TNKS1 and TNKS2, respectively. PARP1/2/TNKS1/2-IN-1 exhibits favorable synergistic antitumor efficacy and induces apoptosis.

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