GENERAL CATALOGUE
PARP1/BRD4-IN-3
HY-169170 · 50 mg
MedChemExpress · Cat: HY-169170
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Manufacturer product page
medchemexpress.com/parp1-brd4-in-3.htmlCatalog No: HY-169170
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
PARP1/BRD4-IN-3 compound HF4 is a potent BRD4 and PARP1 inhibitor with IC50 values of 1210, 2019 nM for BRD4, PARP1, respectively. PARP1/BRD4-IN-3 shows antiproliferative activities. PARP1/BRD4-IN-3 induces apoptosis and cell cycle arrest at G0/G1 phase. PARP1/BRD4-IN-3 causes DNA damage and reduces the protein expression of Rad51. PARP1/BRD4-IN-3 shows antitumor efficacy.
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