GENERAL CATALOGUE
PARPYnD
HY-145749 · 1 mg
MedChemExpress · Cat: HY-145749
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Catalog No: HY-145749
CAS No: 2561483-27-8
Category: Cell Cycle DNA Damage
Pack Size: 1 mg
Brand: MedChemExpress
Description
PARPYnD is a PARP enzyme photoaffinity probe AfBP based on the triple PARP1/2/6 inhibitor AZ9482 HY-119653 , which induces breast cancer Formation of multipolar spindles MPS in cells. PARPYnD inhibits PAPR wih IC50 of 38 nM PARP1 , 6 nM PARP2 , 230 nM PARP6 , respectively. PARPYnD enriches recombinant PARP6 incorporated into cell lysates and inhibits PARP6 in cell-free assays, but it does not label PARP6 in intact cells.
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