Particle Size Analyzers Comparison

Description

Summary of Product Features Comparison Table ​ Fundamentals of Particle Size Analysis ​ 1. Summary of Product Features​ iSpect DIA-10 ​​ Reliable Particle Detection System • Efficient Image Acquisition​​ Unprecedented Functionality and Performance • Trace Sample Measurement ​• Small Dead Volume Three-step Easy Measurement • Autofocus Function for Easy Operation SALD-2300​​ SALD-7500nano ​​​ Wide particle concentration range from 0.1 ppm to 200,000 ppm (20%) • Ideal for paste or changeable samples by dilution​​​​​ Continuous measurement function at minimum 1-second intervals • Ideal for samples that change over time (shifts in the dispersion status) Wide measurement range from 15µL to 300mL • Ideal for small-volume sample measurement​ Compatible with data integrity requirements • Support for LabSolutions system with its proven compatibility with ER/ES regulations (only for SALD-2300)​ Aggregates Sizer ​​ Measures the concentration of 100nm to 10µm aggregates of biopharmaceuticals ​​ • Measures aggregates with small sample amounts • Quantitative evaluation of the aggregation process with the real-time measurement function • Temperature control function (when equipped with the Aggregates Sizer TC temperature control function) 2. Comparison Table Model iSpect DIA-10 SALD-2300 SALD-7500nano​ Aggregates Sizer​ Measurement principle Dynamic image analysis method Laser diffraction method Laser diffraction method Laser diffraction method Definition of particle size Geometrical ​ (equivalent area diameter, maximum particle diameter, etc.) Equivalent spherical diameter Equivalent spherical diameter ​ Equivalent spherical diameter ​ Measurement range 5 to 100 μm 0.017 to 2,500 μm 0.007 to 800 μm 100 nm to 10 μm Measurement method • Wet measurement • Wet measurement • Dry measurement • High concentration measurement • Wet measurement • High concentration measurement • Wet measurement Particle count measurement Yes No No Yes* Shape observation and analysis Yes No No No Distribution basis Count basis Volume basis Volume basis Volume basis Measurement time 10 mins 10 secs 10 secs 10 secs Features • Can confirm particle shape • Can identify a small amount of particles • Can evaluate single particle or aggregate • Wide measurement range • Short measurement time • Wide range of sample types ​ • Wide measurement range • Short measurement time *For biopharmaceuticals only. Conversion from volume concentration to number concentration. 3. Lectures on Particle Size Analysis Lecture on Particle Analysis - Beginners' Course Lecture on Particle Analysis - Hands-on Course Lecture on Particle Analysis - Intermediate Course