GENERAL CATALOGUE
PAT-048
HY-123522 · 50 mg
MedChemExpress · Cat: HY-123522
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medchemexpress.com/pat-048.html
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Catalog No: HY-123522
CAS No: 1359983-15-5
Category: Metabolic Enzyme Protease
Pack Size: 50 mg
Brand: MedChemExpress
Description
PAT-048 is a potent, selective and orally active autotaxin inhibitor, inhibits IL-6 mRNA expression, but shows no effect on autotaxin protein and pulmonary lysophosphatidic acid LPA production in lung fibrosis model. PAT-048 shows an IC50 and IC90 of 20 nM and 200 nM for autotaxin in mouse plasma. PAT-048 reduces dermal fibrosis in vivo.
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