PAX6 Mouse Monoclonal Antibody

Description

EnkiLife offers the PAX6 Mouse Monoclonal Antibody. This antibody reacts with Human species and is suitable for IHC,ELISA,FC application. Alternative Names of Immunogen: AN; AN2; FVH1; MGDA; WAGR; D11S812E. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: IHC 1:200-1:1000,ELISA 1:5000-1:20000,FC 1:200-1:400 Background: This gene encodes paired box gene 6, one of many human homologs of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause ocular disorders such as aniridia and Peter's anomaly. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.