GENERAL CATALOGUE
PB01
HY-170572 · 50 mg
MedChemExpress · Cat: HY-170572
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medchemexpress.com/pb01.html
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Catalog No: HY-170572
CAS No: 368434-78-0
Category: Immunology Inflammation
Pack Size: 50 mg
Brand: MedChemExpress
Description
PB01 is a DPP-4 inhibitor with an IC50 of 15.66 nM. It effectively inhibits high glucose-induced ROS production and mitochondrial superoxide formation while significantly reducing cellular DPP-4 expression. PB01 can also significantly lower blood glucose levels in diabetic mice. Additionally, PB01 demonstrates good safety, exhibiting almost no cytotoxicity at a concentration of 100 ?M. PB01 holds potential for research in the field of diabetes.
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