GENERAL CATALOGUE
PBA-1105
HY-161743 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-161743
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medchemexpress.com/pba-1105.htmlCatalog No: HY-161743
CAS No: 2410081-56-8
Category: Autophagy
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
PBA-1105 is an autophagy-targeting chimera AUTOTAC that induces p62 self-oligomerization. PBA-1105 selectively binds to exposed hydrophobic regions of misfolded proteins, facilitating their degradation via the autophagic pathway. PBA-1105 increases the autophagic flux of Ub-conjugated aggregates.
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