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PBRM1-BD2-IN-5
GENERAL CATALOGUE

PBRM1-BD2-IN-5

HY-151532 · Free Sample (0.1 - 0.2 mg)

MedChemExpress · Cat: HY-151532

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Catalog No: HY-151532
CAS No: 2819989-61-0
Category: Epigenetics
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress

Description

PBRM1-BD2-IN-5 is a potent PBRM1 Bromodomain inhibitor with Kd values of 1.5 ?M and 3.9 ?M for PBRM1-BD2 and PBRM1-BD5, respectively, and an IC50 value of 0.26 ?M for PBRM1-BD2. PBRM1-BD2-IN-5 reduces the binding of full-length PBRM1 within the PBAF complex in cell lysates to acetylated histone peptide. PBRM1-BD2-IN-5 can be used to research anticancer.

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