PD-1/PD-L1-IN-49

Description

PD-1/PD-L1-IN-49 compound 1c is a potent inhibitor of PD-1/PD-L1, with the IC50 of 77 nM. PD-1/PD-L1-IN-49 activates Jurkat T cells, reflecting successful blockade of the PD-1/PD-L1 immune checkpoint.