PD-L1 CRISPR Stable Knockout CT26 Cell Line

Description

PD-L1 and PD-1 form a well-known immune-inhibiting complex that helps prevent the over-activation of the immune system. Studies have shown upregulation of PD-L1 in tumour cells as a countermeasure to suppress immune attacks. However, the extensive molecular mechanism of such interaction has not been thoroughly investigated. PD-L1 CRISPR Stable Knockout CT26 Cell Line presents a useful tool to study PD-1/PD-L1-blocking therapy.