GENERAL CATALOGUE
PD-L1/HDAC-IN-1
HY-172167 · 50 mg
MedChemExpress · Cat: HY-172167
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Manufacturer product page
medchemexpress.com/pd-l1-hdac-in-1.htmlCatalog No: HY-172167
CAS No: 2923313-69-1
Category: Cell Cycle DNA Damage
Pack Size: 50 mg
Brand: MedChemExpress
Description
PD-L1/HDAC-IN-1 Compound 14 is the inhibitor for PD-L1 and HDAC that inhibits PD-1/PD-L1 interaction, HDAC2 and HDAC3 with IC50 of 88.10, 27.98 and 14.47 nM, respectively. PD-L1/HDAC-IN-1 exhibits slight cytotoxicity in MCF-7 IC50=19.34 ?M . PD-L1/HDAC-IN-1 upregulates the expression of PD-L1 and CXCL10, promoting anti-tumour immune response by recruiting T-cell infiltration into TME.
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