PD1 Mouse Monoclonal Antibody

Description

EnkiLife offers the PD1 Mouse Monoclonal Antibody. This antibody reacts with Human species and is suitable for WB,ELISA,FC application. Alternative Names of Immunogen: PDCD1; PD-1; CD279; SLEB2; hPD-1; hPD-l; hSLE1. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2000,ELISA 1:5000-1:20000,FC 1:200-1:400 Background: This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. Research Area: Apoptosis