GENERAL CATALOGUE
PD98059 (Standard)
HY-12028R · 5 mg
MedChemExpress · Cat: HY-12028R
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Catalog No: HY-12028R
CAS No: 167869-21-8
Category: Autophagy
Pack Size: 5 mg
Brand: MedChemExpress
Description
PD98059 Standard is the analytical standard of PD98059. This product is intended for research and analytical applications. PD98059 is a potent and selective MEK inhibitor with an IC50 of 5 AAasAasAAmuM. PD98059 binds to the inactive form of MEK, thereby preventing the activation of MEK1 IC50 of 2-7 AAasAasAAmuM and MEK2 IC50 of 50 AAasAasAAmuM by upstream kinases. PD98059 is a ERK1/2 signaling inhibitor. PD98059 is a ligand for the aryl hydrocarbon receptor AHR , and suppresses TCDD binding IC50 of 4 ?M and AHR transformation IC50 of 1 ?M . PD98059 also inhibits Mycobacterium bovis Bacillus CalmetteGuerin BCG -induced autophagy.
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