

HY-155199 · 50 mg
MedChemExpress · Cat: HY-155199
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Manufacturer product page
medchemexpress.com/pde1-in-5.html
Description
PDE1-IN-5 Compound 10c is a selective PDE1C inhibitor IC50: 15 nM . PDE1-IN-5 has anti- inflammatory activity, and inhibits expression of iNOS, TNF-?, IL-1?, IL-1?, and IL-6 induced by LPS. PDE1-IN-5 has anti-inflammatory bowel disease IBD effects in the dextran sodium sulfate DSS -Induced colitis mice model. PDE1-IN-5 can be used for research of IBD.







