GENERAL CATALOGUE
PDE1-IN-9
HY-169402 · 1 mg
MedChemExpress · Cat: HY-169402
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Catalog No: HY-169402
CAS No: 2982945-41-3
Category: Immunology Inflammation
Pack Size: 1 mg
Brand: MedChemExpress
Description
PDE1-IN-9 Compound 7a is a selective inhibitor for phosphodiesterase 1 PDE1 , that inhibits PDE1C with an IC50 of 11 nM. PDE1-IN-9 reduces mRNA expression of IL-1?, IL-6, TNF-? and iNOS, inhibits the production of nitric oxide NO and reactive oxygen species ROS . PDE1-IN-9 exhibits good metabolic stability in rat liver microsomes.