GENERAL CATALOGUE
PDE4-IN-29
HY-176520 · 50 mg
MedChemExpress · Cat: HY-176520
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Manufacturer product page
medchemexpress.com/pde4-in-29.htmlCatalog No: HY-176520
CAS No: 2815361-45-4
Category: Metabolic Enzyme Protease
Pack Size: 50 mg
Brand: MedChemExpress
Description
PDE4-IN-29 Compound 55 is an orally active and selective PDE4 inhibitor including subtypes such as PDE4A1, PDE4B2, PDE4D3 with IC50s of 5 nM against PDE4D3. PDE4-IN-29 inhibits the degradation of cyclic adenosine monophosphate cAMP , increases intracellular cAMP levels, suppressing the release of inflammatory factors such as TNF-?. PDE4-IN-29 is promising for research of inflammatory diseases including psoriasis, atopic dermatitis, and chronic obstructive pulmonary disease.
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